Purkinje Cell Cytoplasmic Antibody (PCA-2)-related Chorea–Dystonia Syndrome
نویسندگان
چکیده
منابع مشابه
Purkinje Cell Cytoplasmic Antibody (PCA-2)-related Chorea–Dystonia Syndrome
There are several causes of adult-onset chorea, with Huntington’s disease (HD) being the most common. We report a patient who developed a complex movement disorder consisting of chorea and dystonia associated with caudate atrophy on brain magnetic resonance imaging (MRI) because of a paraneoplastic etiology that can be easily confused with HD. He was found to have elevated titers of Purkinje ce...
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IMPORTANCE Purkinje cell cytoplasmic antibody type 1 (PCA-1)-IgG (or anti-Yo) is characteristically detected in women with gynecological or breast adenocarcinoma. We describe 2 unique scenarios occurring in 1 patient: PCA-1 paraneoplastic autoimmunity in a child, and a paraneoplastic neurological disorder in the context of Down syndrome. OBSERVATIONS A child with Down syndrome and a history o...
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ژورنال
عنوان ژورنال: Tremor and Other Hyperkinetic Movements
سال: 2016
ISSN: 2160-8288
DOI: 10.5334/tohm.309